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Journal Article 48

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Gut microbiota 14

gut microbiota 5

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ADT-OH improves intestinal barrier function and remodels the gut microbiota in DSS-induced colitis

Frontiers of Medicine   Pages 972-992 doi: 10.1007/s11684-023-0990-1

Abstract: Moreover, ADT-OH reduced intestinal inflammation by suppressing the nuclear factor kappa-B pathway.In vivo and in vitro results showed that ADT-OH decreased intestinal permeability by increasingIn addition, ADT-OH restored intestinal microbiota dysbiosis characterized by the significantly increasedTransplanting ADT-OH-modulated microbiota can alleviate DSS-induced colitis and negatively regulate the

Keywords： inflammatory bowel disease     ADT-OH     intestinal permeability     gut microbiota    

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Altered intestinal microbiota associated with colorectal cancer

Hong Zhang, Ying Chang, Qingqing Zheng, Rong Zhang, Cheng Hu, Weiping Jia

Frontiers of Medicine 2019, Volume 13, Issue 4,   Pages 461-470 doi: 10.1007/s11684-019-0695-7

Abstract: The gut microbiota plays an important role in the development and progression of colorectal cancer (CRCTo learn more about the dysbiosis of carcinogenesis, we assessed alterations in gut microbiota in patientsreduction in which is a butyrate-producing genera of bacteria, and a significant increase in in the gut microbiota

Keywords： colorectal cancer (CRC)     gut microbiota     intestinal     Eubacterium     Devosia    

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Structural shifts in the intestinal microbiota of rats treated with cyclosporine A after orthotropic

Junjun Jia, Xinyao Tian, Jianwen Jiang, Zhigang Ren, Haifeng Lu, Ning He, Haiyang Xie, Lin Zhou, Shusen Zheng

Frontiers of Medicine 2019, Volume 13, Issue 4,   Pages 451-460 doi: 10.1007/s11684-018-0675-3

Abstract: Understanding the effect of immunosuppressive agents on intestinal microbiota is important to reduceinvestigated the relationship between the commonly used immunosuppressive agent cyclosporine A (CSA) and the intestinalThe intestinal microbiota was assayed by denaturing gradient gel electrophoresis profiles and by usingHence, CSA ameliorates hepatic graft injury and partially restores gut microbiota following LT, and these

Keywords： microbial community     liver transplantation     immunosuppressive agents     cyclosporine A    

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Recent advances in systemic lupus erythematosus and microbiota: from bench to bedside

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 686-700 doi: 10.1007/s11684-022-0957-7

Abstract: Human microbiome, which is mostly composed of microbiota colonized in the gut, skin, and oral cavity,The past decade of research has demonstrated a strong association between microbiota and metabolic diseasesand methodological progress facilitates further microbiota research in SLE.In this review, the latest research about the role and mechanisms of microbiota in SLE and the advancesin the development of diagnostic and therapeutic strategies based on microbiota for SLE were summarized

Keywords： systemic lupus erythematosus     microbiota     biotherapy    

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Multi-Omics Analysis Provides Insight into the Possible Molecular Mechanism of Hay Fever Based on Gut Microbiota Article

Pei Han, Li-Sha Li, Zi-Xi Wang, Lin Xi, Hang Yu, Lin Cong, Zheng-Wei Zhang, Jie Fu, Ran Peng, Li-Bin Pan, Shu-Rong Ma, Xue-Yan Wang, Hong-Tian Wang, Xiang-Dong Wang, Yan Wang, Jin-Lyu Sun, Jian-Dong Jiang

Engineering 2022, Volume 15, Issue 8,   Pages 115-125 doi: 10.1016/j.eng.2021.03.013

Abstract: searched for a possible mechanism from the perspective of the molecular interface between host and microbiotaFurthermore, the expression of intestinal claudin-3 and liver fatty acid binding protein was downregulatedand the gut microbiome (specifically Akkermansia and Helicobacter) may disrupt the intestinal

Keywords： Metabolome     Gut microbiota     Hay fever     Allergic diseases     Intestinal barrier dysfunction    

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Clinical Significance of the Correlation between Changes in the Major Intestinal Bacteria Species and Article

Lingling Tang, Silan Gu, Yiwen Gong, Bo Li, Haifeng Lu, Qiang Li, Ruhong Zhang, Xiang Gao, Zhengjie Wu, Jiaying Zhang, Yuanyuan Zhang, Lanjuan Li

Engineering 2020, Volume 6, Issue 10,   Pages 1178-1184 doi: 10.1016/j.eng.2020.05.013

Abstract: Our previous studies found that H7N9 patients had intestinal dysbiosis.The objective of this study was to investigate changes in the abundance of ten predominant intestinal

Keywords： Intestinal microbiota     COVID-19     SARS-CoV-2    

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Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 239-248 doi: 10.1007/s11684-018-0617-0

Abstract:

The gut microbiota is mainly composed of a diverse population of commensal bacterial species and playsa pivotal role in the maintenance of intestinal homeostasis, immune modulation and metabolism.The influence of the gut microbiota on solid organ transplantation has recently been recognized.In this review, we focused on the recent findings regarding alterations in the microbiota following SBTFurthermore, we explored the potential of the gut microbiota as a microbial marker and/or therapeutic

Keywords： gut microbiota     small bowel transplantation     acute rejection     chronic rejection     mucosal immunity     biomarker     microbiota-targeted therapy    

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Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 87-92 doi: 10.1007/s11684-007-0017-3

Abstract: The aim of this paper is to explore the effect of intestinal ischemia/reperfusion (I/R) injury on leptinAn intestinal I/R injury model of rats was made; the rats were grouped according to the time of afterLeptin and orexin-A respond to intestinal I/R injury in a time-dependent manner, with leptin responding

Keywords： significant difference     intestinal I/R     transcriptase-polymerase     metabolic     central secretory    

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The Biofunctions of Phytochemicals and Their Applications in Farm Animals: The Nrf2/Keap1 System as a Target

Si Qin, De-Xing Hou

Engineering 2017, Volume 3, Issue 5,   Pages 738-752 doi: 10.1016/J.ENG.2017.03.011

Abstract: We then summarize the effects of phytochemicals on the growth performance, meat quality, and intestinalmicrobiota of farm animals via targeting the Nrf 2/Keap1 system.

Keywords： Phytochemical     Biofunction     Nrf 2/Keap1 system     Growth performance     Meat quality     Intestinal microbiota    

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The Fish Microbiota: Research Progress and Potential Applications Review

Yinyin Luan, Ming Li, Wei Zhou, Yuanyuan Yao, Yalin Yang, Zhen Zhang, Einar Ringø, Rolf Erik Olsen, Jihong Liu Clarke, Shouqi Xie, Kangsen Mai, Chao Ran, Zhigang Zhou

Engineering 2023, Volume 29, Issue 10,   Pages 137-146 doi: 10.1016/j.eng.2022.12.011

Abstract:

The gut microbiota plays an important role in host health and diseaseThe intestinal microbiota affects the nutritional metabolism, immunity, and disease resistance of thefish host, while the host regulates the intestinal microbiota in a reciprocal way through both immuneIn this review, we discuss recent progress in fish microbiota research.fundamental research extending our knowledge of host–microbiota interaction in fish.

Keywords： Gut microbiota     Fish     Host–microbiota interaction     Aquaculture    

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Clinical factors associated with composition of lung microbiota and important taxa predicting clinical

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 389-402 doi: 10.1007/s11684-021-0856-3

Abstract: Few studies have described the key features and prognostic roles of lung microbiota in patients withvariance found that positive bacteria lab test results had the strongest independent association with lung microbiotapositive bacteria lab test results, AKI, and plasma MIP-1β level were associated with patients’ lung microbiota

Keywords： severe community-acquired pneumonia     lung microbiota     clinical improvements     7-category ordinal scale    

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Treating Chronic Diseases by Regulating the Gut Microbiota

Bin Hong, Jian-Dong Jiang

Engineering 2022, Volume 18, Issue 11,   Pages 17-20 doi: 10.1016/j.eng.2021.08.015

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Pien Tze Huang Protects Against Non-Alcoholic Steatohepatitis by Modulating the Gut Microbiota and Metabolites

Xianyi Zeng,Xiang Zhang,Hao Su,Hongyan Gou,Harry Cheuk-Hay Lau,Xiaoxu Hu,Ziheng Huang,Yan Li,Jun Yu,

Engineering doi: 10.1016/j.eng.2022.10.010

Abstract: Through the metagenomic sequencing of stool samples, we found that PTH administration restored the gut microbiotaaddition, PTH restored the gut barrier function in mice with steatohepatitis, as evidenced by reduced intestinalWe further confirmed that an intact gut microbiota is necessary for PTH to exhibit anti-steatohepatitisIn conclusion, PTH protects against steatohepatitis development by modulating the gut microbiota and

Keywords： Pien Tze Huang     Non-alcoholic steatohepatitis     Gut barrier function     Gut microbiota    

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Ca-Alginate-Based Janus Capsules with a Pumping Effect for Intestinal-Targeted Controlled Release Article

Shuang Wen, XiaoJie Ju, Wenying Liu, Yuqiong Liu, Xingqun Pu, Zhuang Liu, Wei Wang, Rui Xie, Yousef Faraj, Liangyin Chu

Engineering 2023, Volume 24, Issue 5,   Pages 114-125 doi: 10.1016/j.eng.2022.05.021

Abstract:

A novel intestinal-targeted θ-shaped capsule with a pumping effect for the controlled releaseshell offers improved protection for the encapsulated drug in the stomach environment and excellent intestinal-targetedprovide a potential and novel model for developing responsive pumping controlled-release systems and intestinal-targeted

Keywords： Capsules     Ca-alginate     Intestinal-targeted delivery     Pumping effects     Controlled release    

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Untargeted metabolomic analysis of pregnant women exposure to perfluorooctanoic acid at different degrees

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1628-x

Abstract:

● Metabolome can distinguish pregnant women exposure to PFOA at different degrees.

Keywords： Perfluorooctanoic acid     Exposure     Pregnant women     Metabolomic     GSH     Microbiota metabolism    

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Title Author Date Type Operation

ADT-OH improves intestinal barrier function and remodels the gut microbiota in DSS-induced colitis

Journal Article

Altered intestinal microbiota associated with colorectal cancer

Hong Zhang, Ying Chang, Qingqing Zheng, Rong Zhang, Cheng Hu, Weiping Jia

Journal Article

Structural shifts in the intestinal microbiota of rats treated with cyclosporine A after orthotropic

Junjun Jia, Xinyao Tian, Jianwen Jiang, Zhigang Ren, Haifeng Lu, Ning He, Haiyang Xie, Lin Zhou, Shusen Zheng

Journal Article

Recent advances in systemic lupus erythematosus and microbiota: from bench to bedside

Journal Article

Multi-Omics Analysis Provides Insight into the Possible Molecular Mechanism of Hay Fever Based on Gut Microbiota

Pei Han, Li-Sha Li, Zi-Xi Wang, Lin Xi, Hang Yu, Lin Cong, Zheng-Wei Zhang, Jie Fu, Ran Peng, Li-Bin Pan, Shu-Rong Ma, Xue-Yan Wang, Hong-Tian Wang, Xiang-Dong Wang, Yan Wang, Jin-Lyu Sun, Jian-Dong Jiang

Journal Article

Clinical Significance of the Correlation between Changes in the Major Intestinal Bacteria Species and

Lingling Tang, Silan Gu, Yiwen Gong, Bo Li, Haifeng Lu, Qiang Li, Ruhong Zhang, Xiang Gao, Zhengjie Wu, Jiaying Zhang, Yuanyuan Zhang, Lanjuan Li

Journal Article

Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Journal Article

Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Journal Article

The Biofunctions of Phytochemicals and Their Applications in Farm Animals: The Nrf2/Keap1 System as a Target

Si Qin, De-Xing Hou

Journal Article

The Fish Microbiota: Research Progress and Potential Applications

Yinyin Luan, Ming Li, Wei Zhou, Yuanyuan Yao, Yalin Yang, Zhen Zhang, Einar Ringø, Rolf Erik Olsen, Jihong Liu Clarke, Shouqi Xie, Kangsen Mai, Chao Ran, Zhigang Zhou

Journal Article

Clinical factors associated with composition of lung microbiota and important taxa predicting clinical

Journal Article

Treating Chronic Diseases by Regulating the Gut Microbiota

Bin Hong, Jian-Dong Jiang

Journal Article

Pien Tze Huang Protects Against Non-Alcoholic Steatohepatitis by Modulating the Gut Microbiota and Metabolites

Xianyi Zeng,Xiang Zhang,Hao Su,Hongyan Gou,Harry Cheuk-Hay Lau,Xiaoxu Hu,Ziheng Huang,Yan Li,Jun Yu,

Journal Article

Ca-Alginate-Based Janus Capsules with a Pumping Effect for Intestinal-Targeted Controlled Release

Shuang Wen, XiaoJie Ju, Wenying Liu, Yuqiong Liu, Xingqun Pu, Zhuang Liu, Wei Wang, Rui Xie, Yousef Faraj, Liangyin Chu

Journal Article

Untargeted metabolomic analysis of pregnant women exposure to perfluorooctanoic acid at different degrees

Journal Article